Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740761 | 0.86 | MEN1 (0.39) | GPR119POLBKDM4EHSD11B1FAAH | |
| SCHEMBL30740766 | 0.84 | HSD11B1 (0.38) | NPC1GPR119POLBKDM4EHSD11B1 | |
| SCHEMBL29826172 | 0.82 | GPR119 (0.53) | GPR119FAAH | |
| SCHEMBL30740772 | 0.80 | GPR119 (0.38) | GPR119POLBCHEK2 | |
| SCHEMBL30740770 | 0.80 | GPR119 (0.37) | GPR119POLBKDM4EHSD11B1 | |
| SCHEMBL30740852 | 0.77 | HSD11B1 (0.41) | GPR119POLBKDM4EHSD11B1UCHL1 | |
| SCHEMBL30668743 | 0.77 | GPR119 (0.44) | NPC1GPR119HSD11B1 | |
| SCHEMBL30731233 | 0.76 | GPR119 (0.51) | GPR119KDM4EHSD11B1UCHL1L3MBTL1 | |
| SCHEMBL29223963 | 0.74 | GPR119 (0.48) | NPC1GPR119KDM4EHSD11B1UCHL1 | |
| SCHEMBL31482749 | 0.72 | DYRK1A (0.43) | NPC1GPR119KDM4ECHEK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |