Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826100 | 0.81 | GPR119 (0.56) | GPR119HRH3KDM1A | |
| SCHEMBL27111204 | 0.81 | GPR119 (0.56) | GPR119HRH3KDM1A | |
| SCHEMBL30740740 | 0.81 | TRPV3 (0.39) | ALDH1A1LMNATSHRGPR119NR1H2 | |
| SCHEMBL30740730 | 0.81 | MRGPRX4 (0.46) | ALDH1A1LMNATSHRUCHL1GRM5 | |
| SCHEMBL30740781 | 0.81 | KDM1A (0.44) | ALDH1A1LMNATSHRUCHL1MAPT | |
| SCHEMBL30740755 | 0.78 | LNPEP (0.38) | ALDH1A1LMNAUCHL1GPR119NPSR1 | |
| SCHEMBL30740835 | 0.77 | MAPT (0.42) | HSD11B1UCHL1GPR119NR1H2NR1H3 | |
| SCHEMBL30740793 | 0.77 | NPC1 (0.41) | HSD11B1UCHL1GPR119KDM4EPOLB | |
| SCHEMBL30740726 | 0.76 | GPR119 (0.42) | HSD11B1GPR119KDM4EPOLB | |
| SCHEMBL29223963 | 0.76 | GPR119 (0.48) | HSD11B1ALDH1A1UCHL1GPR119KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |