Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074125 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2SLC6A2SLC6A4SLC6A3KCNA5 | |
| SCHEMBL3068041 | 0.85 | TSHR (0.49) | SMN1; SMN2SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL3071313 | 0.82 | CYP19A1 (0.44) | SMN1; SMN2SLC6A2SLC6A4SLC6A3KCNA5 | |
| SCHEMBL3075817 | 0.80 | ALOX15 (0.48) | SMN1; SMN2SLC6A2SLC6A4SLC6A3NOTUM | |
| SCHEMBL3068944 | 0.79 | RAB9A (0.45) | SMN1; SMN2SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL3067391 | 0.78 | KMT2A (0.51) | SMN1; SMN2RAB9AKCNA5ALDH1A1KDM4E | |
| SCHEMBL3061547 | 0.77 | POLB (0.46) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL6505819 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2SLC6A2SLC6A4SLC6A3KCNA5 | |
| SCHEMBL3103624 | 0.76 | SLC6A2 (0.43) | SMN1; SMN2SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL3079297 | 0.72 | KCNA5 (0.46) | KCNA5LMNATBXAS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | claimed |
| EP-2222169-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-09-01 | — | — | EP | claimed |
| WO-2009063075-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2009-05-22 | — | — | WO | claimed |
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | disclosed |
| EP-2222169-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009063075-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | ATP CAPITAL LP | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | CYP21A2, HAO1, AHR | SMN1; SMN2 2798/4885SLC6A2 3345/4885SLC6A4 3259/4885 |
| US-20100267555-A1 | Fungicidal mixtures II | CBR3, CBR1, NOX3 | SMN1; SMN2 3685/4885SLC6A2 3142/4885SLC6A4 3479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.