SCHEMBL3074283

SCHEMBL3074283

O=Cc1ccc2ccc(O)cc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH5A1 P51649 3/20 0.56
ABAT P80404 3/20 0.56
KDM4E B2RXH2 1/20 0.50
PTGS2 P35354 1/20 0.50
RAB9A P51151 1/20 0.50
ESR1 P03372 4/20 0.48
ESR2 Q92731 4/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 5/20 0.42
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
PTGS1 P23219 1/20 0.41
AOX1 Q06278 1/20 0.41
TRIM24 O15164 1/20 0.41
HPGD P15428 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
DHODH Q02127 1/20 0.41
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19066455 0.94 ALDH5A1 (0.54) ALDH5A1ABATKDM4EPTGS2RAB9A
SCHEMBL29794356 0.93 ALDH5A1 (0.58) ALDH5A1ABATKDM4EPTGS2RAB9A
SCHEMBL658295 0.93 ALDH5A1 (0.58) ALDH5A1ABATKDM4EPTGS2RAB9A
SCHEMBL31473053 0.93 ALDH5A1 (0.58) ALDH5A1ABATKDM4EPTGS2RAB9A
SCHEMBL10331762 0.88 PTGS1 (0.45) ALDH5A1ABATKDM4EPTGS2RAB9A
SCHEMBL1487663 0.86 CYP2A6 (0.52) ALDH5A1ABATKDM4EPTGS2RAB9A
SCHEMBL29433921 0.86 CYP2A6 (0.52) ALDH5A1ABATKDM4EPTGS2RAB9A
SCHEMBL10331765 0.86 ESR1 (0.61) ALDH5A1ABATESR1ESR2CYP1A2
Dimethyl Sulfoxide SCHEMBL28189523 0.83 ALDH5A1 (0.47) ALDH5A1ABATKDM4EPTGS2RAB9A
Dioxane SCHEMBL12004584 0.83 ALDH5A1 (0.47) ALDH5A1ABATKDM4EPTGS2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221700-A Condensed ring aromatic compound, preparation method and application thereof 北京华森英诺生物科技有限公司 2024-06-21 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20170240706-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2017-08-24 US disclosed
US-9230827-B2 Method for forming a resist under layer film and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-01-05 US disclosed
US-9230827-B2 Method for forming a resist under layer film and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-01-05 US disclosed
US-9046764-B2 Resist underlayer film composition, method for producing polymer for resist underlayer film, and patterning process using the resist underlayer film composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-02 US disclosed
US-9046764-B2 Resist underlayer film composition, method for producing polymer for resist underlayer film, and patterning process using the resist underlayer film composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-02 US disclosed
EP-2816409-A1 Method for forming a resist under layer film and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2014-12-24 EP disclosed
US-20140335692-A1 METHOD FOR FORMING A RESIST UNDER LAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-13 US disclosed
US-20140335692-A1 METHOD FOR FORMING A RESIST UNDER LAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-13 US disclosed
US-5326848-A Thermotropic liquid crystal polyester KURARAY CO., LTD. (JP) 1994-07-05 US disclosed
US-5155113-A Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-10-13 US disclosed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP disclosed
EP-0466085-A2 Thermotropic liquid crystal polyester KURARAY CO., LTD. (JP) 1992-01-15 EP disclosed
EP-0180897-B1 5-FLUOROURACIL DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-08-07 EP disclosed
EP-0436902-A1 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-07-17 EP disclosed
US-4983609-A Anticancer agents OTSUKA PHARMACEUTICAL (JP) 1991-01-08 US disclosed
EP-0323441-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed