Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295333 | 1.00 | CA2 (0.54) | CA2CNR1MAPK1MEN1KMT2A | |
| SCHEMBL30744040 | 0.91 | NTRK1 (0.47) | CA2CNR1MAPK1MEN1KMT2A | |
| SCHEMBL21295424 | 0.91 | NTRK1 (0.47) | CA2CNR1MAPK1MEN1KMT2A | |
| SCHEMBL21295536 | 0.85 | KDR (0.61) | MAPK1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL4104406 | 0.82 | CA2 (0.71) | CA2CNR1MAPK1MEN1KMT2A | |
| SCHEMBL21295515 | 0.82 | MCHR1 (0.59) | CA2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL21295431 | 0.81 | STK39 (0.58) | CA2MAPK1MEN1KMT2ATP53 | |
| SCHEMBL21295339 | 0.80 | TP53 (0.63) | MAPK1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL21295375 | 0.79 | TP53 (0.66) | MAPK1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL30743987 | 0.79 | TP53 (0.66) | MAPK1MEN1KMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |