SCHEMBL30744223

SCHEMBL30744223

C=C(C)C(=O)Oc1ccc2cc(C(=O)Oc3ccc(C(=O)O)cc3)ccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.55
KDM4E B2RXH2 1/20 0.49
KMT2A Q03164 6/20 0.48
TDP1 Q9NUW8 3/20 0.48
MEN1 O00255 3/20 0.48
MAPT P10636 3/20 0.48
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.45
HGFAC Q04756 2/20 0.45
ATM Q13315 1/20 0.42
ESR1 P03372 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30744224 1.00 ELANE (0.55) ELANEKDM4EKMT2ATDP1MEN1
SCHEMBL27322408 1.00 ELANE (0.55) ELANEKDM4EKMT2ATDP1MEN1
SCHEMBL11961792 0.94 ELANE (0.56) ELANEKDM4EKMT2ATDP1MEN1
SCHEMBL30337451 0.90 KDM4E (0.60) ELANEKDM4EKMT2ATDP1MEN1
SCHEMBL1319590 0.90 KDM4E (0.60) ELANEKDM4EKMT2ATDP1MEN1
Hydrochloric Acid SCHEMBL1318956 0.88 KDM4E (0.58) ELANEKDM4EKMT2ATDP1MEN1
SCHEMBL13409755 0.88 ELANE (0.64) ELANEKMT2ATDP1MEN1MAPT
SCHEMBL11963929 0.87 KDM4E (0.57) ELANEKDM4EKMT2ATDP1MEN1
SCHEMBL12376709 0.86 ELANE (0.56) ELANEKDM4EKMT2ATDP1MEN1
SCHEMBL23641002 0.85 ELANE (0.50) ELANEKMT2ATDP1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4538305-A1 ATROPISOMER OF 1,1`-BINAPHTHYL DERIVATIVE, POLYMERIZABLE LIQUID CRYSTAL COMPOUND, OPTICAL FILM, IMPAGE DISPLAY DEVICE, AND EYEWEAR Nippon Kayaku Kabushiki Kaisha (JP) 2025-04-16 EP disclosed
US-20250101307-A1 ATROPISOMER OF 1,1'-BINAPHTHYL DERIVATIVE, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL FILM, IMAGE DISPLAY DEVICE, AND EYEWEAR NIPPON KAYAKU KK (JP) 2025-03-27 US disclosed
CN-119301164-A Atropisomers of 1,1' -binaphthyl derivatives, polymerizable liquid crystal compositions, optical films, image display devices and glasses 日本化药株式会社 2025-01-10 CN disclosed
WO-2023243408-A1 ATROPISOMER OF 1,1'-BINAPHTHYL DERIVATIVE, POLYMERIZABLE LIQUID CRYSTAL COMPOUND, OPTICAL FILM, IMPAGE DISPLAY DEVICE, AND EYEWEAR 日本化薬株式会社 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101307-A1 ATROPISOMER OF 1,1'-BINAPHTHYL DERIVATIVE, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL FILM, IMAGE DISPLAY DEVICE, AND EYEWEAR ACVRL1, AMY1A, PARL ELANE 3411/4885KDM4E 4418/4885KMT2A 4113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.