Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744781 | 0.83 | HTR2C (0.54) | KDM4EMAPTMTORTP53CYP1A2 | |
| SCHEMBL30744890 | 0.83 | HTR3A (0.55) | KDM4EALDH1A1CYP1A2HSD17B10LMNA | |
| SCHEMBL30744836 | 0.82 | CSNK2A2 (0.46) | KDM4EALDH1A1HPGDGLAPIK3CA | |
| SCHEMBL30744797 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HPGDGLACYP1A2 | |
| SCHEMBL5241851 | 0.78 | NCF1 (0.64) | KDM4EMAPTPKMALDH1A1HPGD | |
| SCHEMBL30744858 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1HPGDGLACYP1A2 | |
| SCHEMBL30744888 | 0.77 | PRKDC (0.46) | KDM4EALDH1A1HPGDGLACFTR | |
| SCHEMBL29007294 | 0.77 | PIK3CD (0.59) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL30389776 | 0.77 | PIK3CD (0.59) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL30744790 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1HPGDGLACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |