Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744888 | 0.89 | PRKDC (0.46) | KDM4EMEN1ALDH1A1CYP1A2GLA | |
| SCHEMBL30744858 | 0.87 | KDM4E (0.42) | KDM4EMEN1ALDH1A1CYP1A2GLA | |
| SCHEMBL30744790 | 0.86 | KDM4E (0.41) | KDM4EMEN1ALDH1A1CYP1A2GLA | |
| SCHEMBL30744836 | 0.86 | CSNK2A2 (0.46) | KDM4EMEN1ALDH1A1CYP1A2GLA | |
| SCHEMBL30744932 | 0.84 | ALOX15 (0.47) | KDM4EMEN1ALDH1A1CYP1A2GLA | |
| SCHEMBL30744894 | 0.84 | CHEK2 (0.42) | KDM4EMEN1ALDH1A1CYP1A2GLA | |
| SCHEMBL30744890 | 0.79 | HTR3A (0.55) | KDM4EMEN1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL30744781 | 0.79 | HTR2C (0.54) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL30744833 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1CYP1A2GLAHPGD | |
| SCHEMBL31165745 | 0.72 | MEN1 (0.55) | KDM4EMEN1ALDH1A1CYP1A2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |