Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | HTR3B | O95264 | 1/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623818 | 0.88 | KDM4E (0.55) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL30744781 | 0.83 | HTR2C (0.54) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL30744833 | 0.83 | KDM4E (0.55) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL30744836 | 0.82 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL30744797 | 0.79 | KDM4E (0.44) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL30744858 | 0.78 | KDM4E (0.42) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL30744888 | 0.77 | PRKDC (0.46) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL30744932 | 0.77 | ALOX15 (0.47) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL30744894 | 0.77 | CHEK2 (0.42) | HTR3ACSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL30744790 | 0.77 | KDM4E (0.41) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |