Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31726107 | 0.76 | CA12 (0.47) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL31726176 | 0.73 | TSHR (0.40) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL9088493 | 0.72 | NPC1 (0.37) | NPC1RAB9AKDM4ETDP1MEN1 | |
| SCHEMBL31726120 | 0.72 | KDM4E (0.38) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL6068320 | 0.71 | CCNE1 (0.37) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL30002369 | 0.71 | P2RX7 (0.36) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL659694 | 0.71 | ALDH1A1 (0.33) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL659590 | 0.70 | NPC1 (0.31) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL3309453 | 0.70 | CES2 (0.50) | KDM4ETDP1DAOMEN1KMT2A | |
| SCHEMBL2722669 | 0.70 | ALDH1A1 (0.46) | NPC1RAB9AKDM4EHKDC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |