Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744797 | 0.84 | KDM4E (0.44) | ALOX15KDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL30744858 | 0.83 | KDM4E (0.42) | ALOX15TTRKDM4EALDH1A1MEN1 | |
| SCHEMBL30744894 | 0.82 | CHEK2 (0.42) | ALOX15TTRKDM4EALDH1A1MEN1 | |
| SCHEMBL30744790 | 0.82 | KDM4E (0.41) | ALOX15TTRMAPK1KDM4EALDH1A1 | |
| SCHEMBL30744747 | 0.80 | ALOX15 (0.57) | ALOX15TTRKDM4EALDH1A1MEN1 | |
| SCHEMBL30744890 | 0.77 | HTR3A (0.55) | MAPK1KDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL30744888 | 0.77 | PRKDC (0.46) | KDM4EALDH1A1MEN1CYP1A2GLA | |
| SCHEMBL30744836 | 0.76 | CSNK2A2 (0.46) | ALOX15MAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL30744833 | 0.75 | KDM4E (0.55) | ALOX15KDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL30744781 | 0.75 | HTR2C (0.54) | KDM4EMEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |