Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17151081 | 0.86 | LMNA (0.46) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL29953798 | 0.85 | UCHL1 (0.52) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL14240400 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL22726599 | 0.85 | UCHL1 (0.52) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL23530227 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30006360 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL22473361 | 0.82 | PRMT5 (0.43) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30053503 | 0.82 | PDE4B (0.56) | MAPTHTT | |
| SCHEMBL24791835 | 0.82 | PDE4B (0.56) | MAPTHTT | |
| SCHEMBL27168901 | 0.82 | PDE4B (0.56) | MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |