Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953798 | 1.00 | UCHL1 (0.52) | UCHL1ROCK2ALDH1A1RIPK1LMNA | |
| SCHEMBL17151081 | 0.87 | LMNA (0.46) | UCHL1ALDH1A1RIPK1LMNANPSR1 | |
| SCHEMBL14240400 | 0.86 | ALDH1A1 (0.43) | UCHL1ALDH1A1RIPK1LMNANPSR1 | |
| SCHEMBL30745375 | 0.85 | ALDH1A1 (0.45) | UCHL1ALDH1A1RIPK1LMNANPSR1 | |
| SCHEMBL22726571 | 0.84 | UCHL1 (0.41) | UCHL1ROCK2 | |
| SCHEMBL29953613 | 0.84 | UCHL1 (0.41) | UCHL1ROCK2 | |
| SCHEMBL22473361 | 0.83 | PRMT5 (0.43) | UCHL1ALDH1A1RIPK1LMNANPSR1 | |
| SCHEMBL30620837 | 0.82 | ALOX5AP (0.46) | UCHL1ALDH1A1RIPK1LMNANPSR1 | |
| SCHEMBL21198773 | 0.81 | RIPK1 (0.53) | UCHL1ALDH1A1RIPK1LMNANPSR1 | |
| SCHEMBL31226555 | 0.81 | RIPK1 (0.53) | UCHL1ALDH1A1RIPK1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976189-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2024-07-03 | — | — | EP | disclosed |
| WO-2020239658-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2020-12-03 | — | — | WO | disclosed |