Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199855 | 0.79 | KCNN4 (0.42) | HSD11B1PDK1PDK2PDK3PDK4 | |
| SCHEMBL8225791 | 0.79 | CA2 (0.44) | IDO1KAT2BCCR2CFDPTGES2 | |
| SCHEMBL12373152 | 0.78 | P2RX7 (0.35) | IDO1KAT2BCCR2CFDPTGES2 | |
| SCHEMBL30148352 | 0.76 | PDK1 (0.39) | NR3C1NR3C2CFDPGRCA2 | |
| SCHEMBL16579358 | 0.76 | KCNN4 (0.39) | IDO1KAT2BCCR2CFDPTGES2 | |
| SCHEMBL20079605 | 0.76 | CFD (0.33) | IDO1KAT2BCCR2CFDPTGES2 | |
| SCHEMBL11837116 | 0.76 | P2RX7 (0.38) | IDO1KAT2BCCR2CFDPTGES2 | |
| SCHEMBL10748080 | 0.74 | TSHR (0.39) | IDO1KAT2BCFDPTGES2CYP1A2 | |
| Hydrochloric Acid SCHEMBL31409893 | 0.74 | KCNN4 (0.38) | IDO1KAT2BCCR2CFDPTGES2 | |
| SCHEMBL1626668 | 0.74 | PLCG1 (0.44) | SMN1; SMN2PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |