Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29665700 | 0.79 | TUBB1 (0.43) | LMNAHTTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7535556 | 0.79 | TUBB1 (0.43) | LMNAHTTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4247206 | 0.76 | HTR6 (0.58) | HTTSMN1; SMN2TP53HTR6KDM4E | |
| SCHEMBL24458142 | 0.75 | TUBB1 (0.39) | LMNAHTTALDH1A1MAPK1RAB9A | |
| SCHEMBL29665751 | 0.75 | TUBB1 (0.39) | LMNAHTTALDH1A1MAPK1RAB9A | |
| SCHEMBL7536230 | 0.75 | HTT (0.41) | LMNAHTTALDH1A1MAPK1RAB9A | |
| SCHEMBL24458182 | 0.74 | HTT (0.41) | LMNAHTTALDH1A1MAPK1MAOB | |
| SCHEMBL21760970 | 0.73 | SMN1; SMN2 (0.51) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27020044 | 0.73 | LMNA (0.45) | LMNAHTTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28835130 | 0.73 | ALDH1A1 (0.50) | HTTSMN1; SMN2ALDH1A1HTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | ABCG2, ABCB1, ARSA | LMNA 992/4885HTT 311/4885SMN1; SMN2 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.