Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.76 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.68 |
| ▸ | MAOB | P27338 | 7/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000294 | 0.87 | PTPRZ1 (1.00) | PTPRZ1MAOBCA12CA1CA2 | |
| SCHEMBL3274502 | 0.84 | PTPRZ1 (0.72) | PTPRZ1MAOBMMP1MMP2MMP9 | |
| SCHEMBL2788803 | 0.82 | CA2 (0.59) | PTPRZ1PARP10CA12CA1CA2 | |
| SCHEMBL30576796 | 0.80 | MAOB (1.00) | PARP10MAOBNR4A2 | |
| SCHEMBL22721364 | 0.80 | PARP10 (0.76) | PARP10MAOBPARP15PARP14F2 | |
| SCHEMBL31530352 | 0.79 | PARP10 (0.73) | PARP10MAOBPARP15PARP14F2 | |
| SCHEMBL5431855 | 0.78 | KIF11 (0.64) | CA12CA1CA2CA9 | |
| SCHEMBL6002339 | 0.77 | PTPRZ1 (0.78) | PTPRZ1MAOBCA12CA1CA2 | |
| SCHEMBL30745904 | 0.77 | PTPRZ1 (0.72) | PTPRZ1PARP10MAOBPARP15PARP14 | |
| SCHEMBL11117974 | 0.75 | PARP10 (0.83) | PARP10MAOBF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |