Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 12/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306961 | 0.88 | GABRA1 (0.49) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL8288797 | 0.78 | BCHE (0.38) | BCHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL28813437 | 0.74 | KMT2A (0.41) | BCHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL15252478 | 0.74 | BCHE (0.40) | BCHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL5184141 | 0.73 | BCHE (0.47) | BCHEMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL15252551 | 0.71 | PDE4B (0.38) | BCHEMEN1KMT2A | |
| SCHEMBL13559889 | 0.71 | BCHE (0.41) | BCHEMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL27927848 | 0.71 | USP2 (0.39) | BCHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL28970109 | 0.70 | UCHL1 (0.37) | BCHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL29168570 | 0.68 | BCHE (0.35) | BCHEMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907338-B | Nitrogen-containing polycyclic condensed ring compound, pharmaceutical composition, preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |