Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26649124 | 1.00 | CHRM2 (0.41) | CHRM2CHRM3SLC6A4SLC6A3ALOX5 | |
| SCHEMBL31375641 | 0.69 | CHRM2 (0.37) | CHRM2CHRM3SLC6A4SLC6A3BACE1 | |
| SCHEMBL21780752 | 0.68 | SLC6A3 (0.43) | SLC6A4SLC6A3ALOX5OPRM1OPRL1 | |
| SCHEMBL30207550 | 0.68 | SLC6A3 (0.39) | CHRM2CHRM3SLC6A4SLC6A3ALOX5 | |
| SCHEMBL31098700 | 0.68 | SLC6A3 (0.39) | CHRM2CHRM3SLC6A4SLC6A3ALOX5 | |
| SCHEMBL31098644 | 0.68 | SLC6A3 (0.39) | CHRM2CHRM3SLC6A4SLC6A3ALOX5 | |
| SCHEMBL27173342 | 0.68 | SLC6A3 (0.39) | CHRM2CHRM3SLC6A4SLC6A3ALOX5 | |
| SCHEMBL4596721 | 0.65 | CHRM2 (0.37) | CHRM2CHRM3SLC6A4SLC6A3BACE1 | |
| SCHEMBL4596366 | 0.65 | CHRM2 (0.37) | CHRM2CHRM3SLC6A4SLC6A3BACE1 | |
| SCHEMBL16409436 | 0.64 | SLC6A3 (0.43) | CHRM2CHRM3SLC6A4SLC6A3BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522583-A2 | PI3K ALPHA INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220131-A2 | PI3Kα INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |