Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26649124 | 0.69 | CHRM2 (0.41) | CHRM2CHRM3BACE1ADAMTS5MMP2 | |
| SCHEMBL30747360 | 0.69 | CHRM2 (0.41) | CHRM2CHRM3BACE1ADAMTS5MMP2 | |
| SCHEMBL4599454 | 0.66 | BACE1 (0.47) | CHRM2CHRM3BACE1ADAMTS5MMP2 | |
| SCHEMBL16409436 | 0.64 | SLC6A3 (0.43) | CHRM2CHRM3BACE1HSD11B1SLC6A4 | |
| SCHEMBL8265409 | 0.62 | BACE1 (0.47) | BACE1 | |
| SCHEMBL4596366 | 0.60 | CHRM2 (0.37) | CHRM2CHRM3BACE1SLC6A4SLC6A3 | |
| SCHEMBL4596721 | 0.60 | CHRM2 (0.37) | CHRM2CHRM3BACE1SLC6A4SLC6A3 | |
| SCHEMBL16108316 | 0.60 | CHRM3 (0.40) | CHRM2CHRM3BACE1RAB9ADPP4 | |
| SCHEMBL31098644 | 0.60 | SLC6A3 (0.39) | CHRM2CHRM3SLC6A4SLC6A3DPP4 | |
| SCHEMBL31098700 | 0.60 | SLC6A3 (0.39) | CHRM2CHRM3SLC6A4SLC6A3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486992-A | PI3K alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2025-02-18 | — | — | CN | disclosed |