SCHEMBL30747787

SCHEMBL30747787

O=Cc1ccc(-c2ccc(C=O)cn2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.56
KCNJ1 P48048 1/20 0.43
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HPGD P15428 3/20 0.42
MITF O75030 1/20 0.42
KLF5 Q13887 1/20 0.42
DRD1 P21728 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD5 P21918 1/20 0.40
DRD3 P35462 1/20 0.40
CYP2A6 P11509 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH5A1 P51649 1/20 0.39
ABAT P80404 1/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28682644 1.00 CYP11B1 (0.56) CYP11B1KCNJ1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL13568531 0.88 ALDH5A1 (0.54) CYP11B1ALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL2322298 0.88 KDM4E (0.54) CYP11B1ALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL9805366 0.88 NPC1 (0.49) CYP11B1KCNJ1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL30578701 0.88 KDM4E (0.54) CYP11B1ALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL4417307 0.88 HSD17B10 (0.54) CYP11B1ALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL13527931 0.88 CYP11B1 (0.48) CYP11B1KCNJ1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL4425760 0.88 ALDH1A1 (0.54) CYP11B1ALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL13536764 0.88 CYP11B1 (0.51) CYP11B1KCNJ1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL30382878 0.88 LDHA (0.52) CYP11B1ALDH1A1CYP2A6LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430770-B Light response oxidase material based on COF, and preparation method and application thereof 四川大学 2024-02-23 CN claimed
CN-117430770-A Light response oxidase material based on COF, and preparation method and application thereof 四川大学 2024-01-23 CN claimed
CN-117430770-B Light response oxidase material based on COF, and preparation method and application thereof 四川大学 2024-02-23 CN disclosed
CN-117430770-B Light response oxidase material based on COF, and preparation method and application thereof 四川大学 2024-02-23 CN disclosed
CN-117430770-A Light response oxidase material based on COF, and preparation method and application thereof 四川大学 2024-01-23 CN disclosed
CN-117430770-A Light response oxidase material based on COF, and preparation method and application thereof 四川大学 2024-01-23 CN disclosed