Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 4/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5910616 | 0.69 | KDM4E (0.33) | TDP1 | |
| SCHEMBL4809948 | 0.67 | PTGS1 (0.42) | TDP1MAPK1ALDH1A1CYP3A4TAAR1 | |
| SCHEMBL17801704 | 0.65 | LTA4H (0.36) | RETTDP1MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL28826421 | 0.65 | IDO1 (0.38) | TDP1MAPK1ALDH1A1CYP3A4TAAR1 | |
| SCHEMBL10841242 | 0.65 | ALDH1A1 (0.46) | TDP1MAPK1ALDH1A1MAOBPOLB | |
| SCHEMBL11593733 | 0.65 | KDM4E (0.32) | TDP1 | |
| SCHEMBL4868046 | 0.62 | TDP1 (0.52) | TDP1MAPK1ALDH1A1CYP3A4TAAR1 | |
| SCHEMBL3044851 | 0.61 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4TAAR1 | |
| SCHEMBL8746062 | 0.61 | CYP19A1 (0.74) | TDP1MAPK1ALDH1A1CYP3A4TAAR1 | |
| SCHEMBL1824702 | 0.60 | MAOB (0.55) | ALDH1A1CYP3A4TAAR1MAOBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |