Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748650 | 0.82 | NCF1 (0.42) | HTR1AHTR2AHTR2CSLC6A4 | |
| SCHEMBL25257753 | 0.81 | POLB (0.48) | POLBUSP2LMNATSHRHTR1A | |
| SCHEMBL13769597 | 0.80 | HTR3A (0.54) | POLBUSP2LMNATSHRHTR1A | |
| SCHEMBL31373558 | 0.79 | ADRB2 (0.43) | POLBUSP2LMNATSHRHTR1A | |
| SCHEMBL31373467 | 0.79 | ADRB2 (0.43) | POLBUSP2LMNATSHRHTR1A | |
| SCHEMBL3560188 | 0.79 | HTR2A (0.63) | LMNATSHRHTR1AADRB2HTR2A | |
| SCHEMBL25296198 | 0.79 | TSHR (0.50) | POLBUSP2LMNATSHRHTR1A | |
| SCHEMBL30600597 | 0.79 | HTR2A (0.63) | LMNATSHRHTR1ACCR1CCR5 | |
| SCHEMBL24336747 | 0.78 | PIM1 (0.58) | POLBUSP2LMNATSHRHTR1A | |
| Hydrochloric Acid SCHEMBL4008999 | 0.78 | HTR2A (0.61) | POLBUSP2LMNATSHRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |