Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748569 | 0.82 | POLB (0.47) | HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL31373455 | 0.81 | ADRB2 (0.39) | PLAUMCHR1NOS3NOS1FFAR2 | |
| SCHEMBL30600597 | 0.79 | HTR2A (0.63) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL30788618 | 0.73 | GRIN2D (0.50) | NOS3 | |
| SCHEMBL17609530 | 0.73 | GRIN2D (0.50) | NOS3 | |
| SCHEMBL23123094 | 0.73 | KEAP1 (0.44) | SLC6A4FFAR2 | |
| SCHEMBL22969399 | 0.71 | HTR3A (0.42) | MCHR1 | |
| SCHEMBL5092004 | 0.71 | KEAP1 (0.60) | SLC6A4DRD2FFAR2 | |
| SCHEMBL31373596 | 0.70 | ADRB2 (0.33) | BACE1MCHR1NOS3NOS1FFAR2 | |
| SCHEMBL22964660 | 0.70 | KEAP1 (0.42) | SLC6A4FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |