SCHEMBL30748783

SCHEMBL30748783

CC1(C)C(=O)N(c2ccc(N3CCOCC3)cc2)c2nc(CO[Si](C)(C)C(C)(C)C)nc(Cl)c21

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AGXT P21549 1/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 2/20 0.33
RAD51 Q06609 1/20 0.32
MTOR P42345 2/20 0.31
USP2 O75604 1/20 0.31
GAA P10253 1/20 0.31
SRC P12931 1/20 0.31
FLT3 P36888 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP3A4 P08684 1/20 0.31
PARP14 Q460N5 1/20 0.31
PTH1R Q03431 2/20 0.31
SLC16A3 O15427 1/20 0.31
SLC16A1 P53985 1/20 0.31
MCTS1 Q9ULC4 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748935 0.90 AGXT (0.37) AGXTMAPTALDH1A1USP2GAA
SCHEMBL30748750 0.89 MTOR (0.36) ALDH1A1RAD51MTORGAACYP3A4
SCHEMBL31691365 0.88 MAPT (0.33) AGXTMAPTL3MBTL1ALDH1A1RAD51
SCHEMBL31691437 0.88 MAPT (0.32) AGXTMAPTL3MBTL1ALDH1A1RAD51
SCHEMBL30748847 0.88 ELANE (0.33)
SCHEMBL31691354 0.87 AGXT (0.33) AGXTMAPTL3MBTL1ALDH1A1USP2
SCHEMBL30748732 0.86 TRPV1 (0.32) PTH1R
SCHEMBL30749058 0.86 ADORA3 (0.36) AGXTMAPTL3MBTL1ALDH1A1GAA
SCHEMBL30748976 0.85 SYK (0.36) AGXTL3MBTL1ALDH1A1CYP3A4MRGPRX4
SCHEMBL30748860 0.84 RAD52 (0.33) AGXTMAPTALDH1A1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT AGXT 955/4885MAPT 3029/4885L3MBTL1 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.