SCHEMBL30749128

SCHEMBL30749128

CC1(C)CN(c2ccc(OC3CCCCC3)cn2)c2nc(CO)ncc21

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM4 P08173 1/20 0.40
ACACB O00763 6/20 0.36
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35
NPY5R Q15761 1/20 0.35
ABL1 P00519 2/20 0.34
GPR119 Q8TDV5 1/20 0.33
ACACA Q13085 1/20 0.32
GRM2 Q14416 1/20 0.30
GRM5 P41594 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748909 0.80 ACACB (0.37) CHRM4ACACBPDGFRBPDGFRA
SCHEMBL30749061 0.80 CHRM4 (0.30) CHRM4
SCHEMBL30748853 0.70 POLB (0.36)
SCHEMBL30748885 0.68 TNK2 (0.33) ACACBABL1GRM2ALDH1A1TSHR
SCHEMBL30749053 0.67 ALDH1A1 (0.48) ALDH1A1
SCHEMBL30749066 0.67 CHRM4 (0.34) CHRM4GRM5
SCHEMBL30749012 0.64 PDE4B (0.40) CHRM4GRM5
SCHEMBL4021756 0.61 MCHR1 (0.45) ACACBPDGFRBPDGFRAABL1ACACA
SCHEMBL12949399 0.61 CHRM4 (0.49) CHRM4PDGFRBPDGFRAABL1
SCHEMBL21158012 0.60 ABCB11 (0.40) CHRM4ACACBPDGFRBPDGFRAACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT CHRM4 4607/4885ACACB 1127/4885PDGFRB 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.