Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | MB | P02144 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10217893 | 0.94 | NOX1 (0.67) | ALDH1A1KMT2AMEN1MAPK1PTGS2 | |
| SCHEMBL7044090 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1MAPK1PTGS2 | |
| SCHEMBL7044085 | 0.91 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1MAPK1PTGS2 | |
| SCHEMBL11227392 | 0.89 | KMT2A (0.59) | ALDH1A1KMT2AMEN1MAPK1PTGS2 | |
| SCHEMBL3959278 | 0.84 | SMN1; SMN2 (0.64) | ALDH1A1KMT2AMEN1MAPK1MAPT | |
| SCHEMBL5026270 | 0.84 | SMN1; SMN2 (0.64) | ALDH1A1KMT2AMEN1MAPK1MAPT | |
| SCHEMBL4910102 | 0.83 | SMN1; SMN2 (0.57) | ALDH1A1KMT2AMEN1MAPK1PTGS2 | |
| SCHEMBL861674 | 0.83 | SMN1; SMN2 (0.84) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL836968 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1MAPK1PTGS2 | |
| SCHEMBL27644436 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1MAPK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130872-B | Preparation method of 3-trifluoromethyl substituted indole | 江西师范大学 | 2018-01-30 | — | — | CN | claimed |
| US-11932601-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| EP-3746421-B1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2023-11-29 | — | — | EP | disclosed |
| EP-3795572-B1 | DARUNAVIR PROPIONATE SOLVATE | LAURUS LABS LTD (IN) | 2023-11-15 | — | — | EP | disclosed |
| CN-116848100-A | NOTCH inhibitors and uses thereof | 干细胞协同疗法有限责任公司 | 2023-10-03 | — | — | CN | disclosed |
| US-20230119740-A1 | THERAPEUTIC COMPOUNDS AND METHODS | GENENTECH, INC. (US) | 2023-04-20 | — | — | US | disclosed |
| CN-112574054-B | Efficient nitriding reagent and application thereof | 北京大学 | 2022-10-14 | — | — | CN | disclosed |
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2022-09-01 | — | — | US | disclosed |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| EP-3510024-B1 | PYRIDYL SUBSTITUTED INDOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-17 | — | — | EP | disclosed |
| EP-0699743-A2 | Electrorheological fluids containing polar solids and organic semiconductors | THE LUBRIZOL CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5435932-A | Polyanilines, clutches, brakes, valves, dampers | THE LUBRIZOL CORPORATION (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0563342-A1 | ELECTRORHEOLOGICAL FLUIDS CONTAINING ELECTRONICALLY CONDUCTIVE POLYMERS | The Lubrizol Corporation (US) | 1993-10-06 | — | — | EP | disclosed |
| WO-1993007243-A1 | ELECTRORHEOLOGICAL FLUIDS CONTAINING ELECTRONICALLY CONDUCTIVE POLYMERS | THE LUBRIZOL CORPORATION (US) | 1993-04-15 | — | — | WO | disclosed |
| US-4735948-A | (1H-tetrazol-5-yl)-2(1H)-quinolinones and-naphthyridones and antiallergic use thereof | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0120484-B1 | (1H-TETRAZOL-5-YL)TETRAZOLO (1,5-A)-QUINOLINES AND RELATED COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-22 | — | — | EP | disclosed |
| EP-0120483-B1 | (1H-TETRAZOL-5-YL)-2(1H)-QUINOLINONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-01 | — | — | EP | disclosed |
| US-4540786-A | Preparation of 2-chloro-3-cyano-quinolines | THE DOW CHEMICAL COMPANY (US) | 1985-09-10 | — | — | US | disclosed |
| US-4496569-A | Antiallergic (1H-tetrazol-5-yl)tetrazolo[1,5-a]quinolines and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0120484-A1 | (1H-tetrazol-5-yl)tetrazolo (1,5-a)-quinolines and related compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230119740-A1 | THERAPEUTIC COMPOUNDS AND METHODS | PCK1, SLC5A1, PFKFB1 | ALDH1A1 345/4885KMT2A 2182/4885MEN1 2261/4885 |
| US-11932601-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | ALDH1A1 219/4885KMT2A 1557/4885MEN1 3659/4885 |
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | ALDH1A1 219/4885KMT2A 1557/4885MEN1 3659/4885 |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | RNF114, RNF4, RNF168 | ALDH1A1 2969/4885KMT2A 501/4885MEN1 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.