Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27170833 | 1.00 | LRRK2 (0.51) | LRRK2ALDH1A1DCTPP1MAP4K1LMNA | |
| SCHEMBL27170795 | 0.83 | LRRK2 (0.44) | LRRK2ALDH1A1DCTPP1MAP4K1LMNA | |
| SCHEMBL17573286 | 0.82 | LRRK2 (0.70) | LRRK2ALDH1A1LMNA | |
| SCHEMBL1905445 | 0.78 | MAPT (0.48) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL27170759 | 0.78 | ALDH1A1 (0.42) | LRRK2ALDH1A1DCTPP1LMNAMEN1 | |
| SCHEMBL2453453 | 0.77 | MAPT (0.59) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL27170782 | 0.77 | ALDH1A1 (0.45) | LRRK2ALDH1A1DCTPP1LMNAMEN1 | |
| SCHEMBL25366939 | 0.76 | ALDH1A1 (0.41) | LRRK2ALDH1A1DCTPP1LMNAMEN1 | |
| SCHEMBL27170654 | 0.75 | POLB (0.44) | LRRK2ALDH1A1DCTPP1LMNAMEN1 | |
| SCHEMBL27170674 | 0.75 | KDM4E (0.41) | LRRK2ALDH1A1DCTPP1MAP4K1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083853-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, INC. | 2024-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083853-A1 | HSD17B13 INHIBITORS AND USES THEREOF | HSD17B3, HSD17B11, HSD17B1 | LRRK2 4153/4885ALDH1A1 247/4885DCTPP1 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.