SCHEMBL30749657

SCHEMBL30749657

C=C(C(=O)N(CCC)CCC)c1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.42
ERBB2 P04626 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MLYCD O95822 1/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30749646 0.86 OPRM1 (0.44) ALDH1A1NPC1L3MBTL1KDM4EMAOA
SCHEMBL10641881 0.81 HPGD (0.47) EGFRERBB2CA12CA1CA9
SCHEMBL27300688 0.77 MAOA (0.49) CA1ALDH1A1POLBMAOAMAOB
SCHEMBL29209361 0.74 TMEM97 (0.50) NPC1L3MBTL1POLBMEN1KMT2A
SCHEMBL25405722 0.72 KMT2A (0.49) NPC1MEN1KMT2ASMN1; SMN2TSPO
SCHEMBL12841554 0.71 ALDH1A1 (0.47) CA1ALDH1A1KDM4EPOLBGAA
SCHEMBL2080074 0.70 CES2 (0.52) CA1ALDH1A1NPC1L3MBTL1KDM4E
SCHEMBL28013721 0.70 ALDH1A1 (0.45) ALDH1A1NPC1KDM4EPOLBGAA
SCHEMBL11751676 0.69 GSK3B (0.53) CA12CA1CA9ALDH1A1NPC1
SCHEMBL28409458 0.69 EGFR (0.65) EGFRERBB2ALDH1A1NPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510291-A Preparation method of acrylamide compound 昆明理工大学 2024-02-06 CN disclosed