Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751 | 0.77 | GAA (0.43) | NOS3NOS1NOS2 | |
| SCHEMBL10607707 | 0.77 | GAA (0.33) | — | |
| SCHEMBL940875 | 0.76 | THRB (0.30) | — | |
| Hydrochloric Acid SCHEMBL2957423 | 0.76 | GAA (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL1408287 | 0.72 | KDM1A (0.31) | — | |
| Hydrochloric Acid SCHEMBL28814652 | 0.71 | KDM1A (0.32) | — | |
| SCHEMBL2163195 | 0.71 | GAA (0.37) | — | |
| SCHEMBL14042739 | 0.70 | MAOA (0.45) | — | |
| SCHEMBL13246762 | 0.70 | MAOA (0.45) | — | |
| SCHEMBL4451124 | 0.69 | KDM1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807479-B1 | SHALE HYDRATION INHIBITION AGENT AND METHOD OF USE | MI LLC (US) | 2012-08-22 | — | — | EP | claimed |
| US-20100160681-A1 | Chiral phosphoramides, chiral N-phosphonimines and methods for forming the same | NOWA PHARMACEUTICALS, CO., LTD. (CN) | 2010-06-24 | — | — | US | claimed |
| WO-2009000202-A1 | CHIRAL PHOSPHORAMIDES, CHIRAL N-PHOSPHONIMINES AND METHODS FOR FORMING THE SAME | NOWA PHARMACEUTICALS CO., LTD (CN) | 2008-12-31 | — | — | WO | claimed |
| US-20100160681-A1 | Chiral phosphoramides, chiral N-phosphonimines and methods for forming the same | NOWA PHARMACEUTICALS, CO., LTD. (CN) | 2010-06-24 | — | — | US | disclosed |
| EP-2125687-A1 | PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS | E. I. Du Pont de Nemours and Company (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2009000202-A1 | CHIRAL PHOSPHORAMIDES, CHIRAL N-PHOSPHONIMINES AND METHODS FOR FORMING THE SAME | NOWA PHARMACEUTICALS CO., LTD (CN) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008079218-A1 | PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |
| EP-0244778-B1 | MONO-TERTIARY-ALKYLATED TOLUENEDIISO-CYANATES AND DERIVATIVES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0244778-A1 | Mono-tertiary-alkylated toluenediiso-cyanates and derivatives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1987-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160681-A1 | Chiral phosphoramides, chiral N-phosphonimines and methods for forming the same | PHOSPHO1, PNP, CDK2 | NOS3 2893/4885NOS1 2053/4885NOS2 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.