SCHEMBL307530

SCHEMBL307530

COc1cccc(C2=NC(c3ccccc3Cl)(n3c(-c4ccccc4Cl)nc(-c4cccc(OC)c4)c3-c3cccc(OC)c3)N=C2c2cccc(OC)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.37
TEK Q02763 1/20 0.37
ADORA2A P29274 6/20 0.36
ADORA1 P30542 5/20 0.36
PDE2A O00408 1/20 0.36
DPP4 P27487 2/20 0.35
PIK3CD O00329 1/20 0.35
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
PDE4B Q07343 1/20 0.34
ALDH1A3 P47895 1/20 0.34
PIK3CG P48736 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16355183 0.96 MAPK10 (0.35) PDE10ATEKADORA2AADORA1PDE2A
SCHEMBL16355184 0.93 PIK3CD (0.36) PDE10AADORA2AADORA1PDE2ADPP4
SCHEMBL16746559 0.92 CASR (0.37) ADORA2AADORA1PIK3CDNR1H2NR1H3
SCHEMBL16355187 0.86 KDM4E (0.43) TEKADORA1
SCHEMBL16355186 0.86 KDM4E (0.43) TEKADORA1
SCHEMBL3101056 0.86 KDM4E (0.39) PDE10ATEKPDE2APIK3CD
SCHEMBL30358508 0.86 KDM4E (0.39) PDE10ATEKPDE2APIK3CD
SCHEMBL23816930 0.85 FABP4 (0.35)
SCHEMBL30358507 0.84 KDM4E (0.38) PDE10ATEKADORA2AADORA1PDE2A
SCHEMBL3086363 0.84 KDM4E (0.38) PDE10ATEKADORA2AADORA1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317942-A1 THIOL-CONTAINING COMPOSITION, PHOTOSETTING COMPOSITION, AND THERMOSETTING COMPOSITION RESONAC CORPORATION (JP) 2024-09-26 US disclosed
EP-4375302-A1 THIOL-CONTAINING COMPOSITION, PHOTOCURABLE COMPOSITION, AND THERMOSETTING COMPOSITION Resonac Corporation (JP) 2024-05-29 EP disclosed
WO-2024008805-A1 HETEROAROMATIC KETONES AND THEIR USE IN RADICAL AND CATIONIC POLYMERIZATION PHOSUMA PHOTONIC & SUSTAINABLE MATERIALS GMBH (DE) 2024-01-11 WO disclosed
WO-2023003011-A1 THIOL-CONTAINING COMPOSITION, PHOTOCURABLE COMPOSITION, AND THERMOSETTING COMPOSITION 昭和電工株式会社 2023-01-26 WO disclosed
EP-2899241-B1 PHOTOPOLYMERIZATION METHOD, INK SET, IMAGE FORMATION METHOD, INK COMPOSITION, AND PHOTOPOLYMERIZATION INITIATOR AND WATER-SOLUBLE BIIMIDAZOLE USED THEREIN FUJIFILM CORP (JP) 2019-08-28 EP disclosed
EP-2154162-B1 REACTIVE URETHANE COMPOUND HAVING ETHER BOND, CURABLE COMPOSITION AND CURED MATERIAL SHOWA DENKO KK (JP) 2019-07-17 EP disclosed
US-9371460-B2 Photopolymerization method, ink set, ink composition, and water-soluble biimidazole FUJIFILM CORPORATION (JP) 2016-06-21 US disclosed
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
EP-1478668-B1 THIOL COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPOSITION AND PHOTOSENSITIVE COMPOSITION SHOWA DENKO KK (JP) 2013-04-10 EP disclosed
EP-1870771-A2 Photosensitive paste composition, barrier rib prepared using the composition and plasma display panel comprising the barrier rib Samsung SDI Co., Ltd. (KR) 2007-12-26 EP disclosed
EP-1031579-B1 Photopolymerization initiator for color filter, photosensitive coloring composition, and color filter SHOWA DENKO KK (JP) 2005-07-27 EP disclosed
US-20050153231-A1 Thiol compound, photopolymerization initiator composition and photosensitive composition SHOWA DENKO K.K. (JP) 2005-07-14 US disclosed
US-20040157140-A1 Photosensitive coloring composition, color filter using the composition and method of producing the same SHOWA DENKO K.K. (JP) 2004-08-12 US disclosed
US-6455207-B1 COLOR FILTER WITH PIXELS ON TRANSPARENT SUBSTRATE COMPRISING PHOTOSENSITIVE COLORING COMPOSITION COMPRISING TRANSPARENT POLYMER SOLUBLE IN SOLVENT OR AQUEOUS ALKALINE SOLUTION, UNSATURATED COMPOUND, PIGMENT, PHOTOPOLYMERIZATION INITIATOR SHOWA DENKO KABUSHIKI KAISHA (JP) 2002-09-24 US disclosed
EP-1062546-A1 PROCESS FOR THE CONTINUOUS LIQUID PROCESSING OF PHOTOSENSITIVE COMPOSITIONS HAVING REDUCED LEVELS OF RESIDUES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2000-12-27 EP disclosed
EP-1031579-A2 Photopolymerization initiator for color filter, photosensitive coloring composition, and color filter SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-08-30 EP disclosed
WO-1999046644-A1 PROCESS FOR THE CONTINUOUS LIQUID PROCESSING OF PHOTOSENSITIVE COMPOSITIONS HAVING REDUCED LEVELS OF RESIDUES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-09-16 WO disclosed
US-4749796-A PHOTORESISTS HODOGAYA CHEMICAL CO., LTD. (JP) 1988-06-07 US disclosed
EP-0184114-A1 A xanthene derivative, a production process of the same and a composite for giving an image which includes the same HODOGAYA CHEMICAL CO., LTD. (JP) 1986-06-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE JAK1, SETDB1, CCNI PDE10A 3542/4885TEK 4071/4885ADORA2A 2944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.