Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 16/20 | 0.65 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.53 |
| ▸ | GABRE | P78334 | 1/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.53 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153416 | 1.00 | HCAR3 (0.65) | HCAR3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2863008 | 0.86 | HCAR3 (0.61) | HCAR3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL82675 | 0.81 | HCAR3 (0.68) | HCAR3HCAR2 | |
| SCHEMBL29505896 | 0.81 | HCAR3 (0.67) | HCAR3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL158601 | 0.81 | HCAR3 (0.67) | HCAR3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14341697 | 0.80 | HCAR3 (0.76) | HCAR3GABRPGABRDGABRA1GABRB1 | |
| Ammonia Solution, Strong SCHEMBL28249483 | 0.79 | HCAR3 (0.65) | HCAR3GABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL5789616 | 0.79 | HCAR3 (0.65) | HCAR3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2664544 | 0.79 | HCAR3 (1.00) | HCAR3 | |
| SCHEMBL10033268 | 0.79 | HCAR3 (0.64) | HCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285533-B | CD47/SIRP alpha small molecule inhibitor, application thereof and anti-tumor pharmaceutical composition | 四川省医学科学院·四川省人民医院 | 2024-01-30 | — | — | CN | disclosed |
| CN-117285533-A | CD47/SIRP alpha small molecule inhibitor, application thereof and anti-tumor pharmaceutical composition | 四川省医学科学院·四川省人民医院 | 2023-12-26 | — | — | CN | disclosed |