Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.42 |
| ▸ | ABAT | P80404 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668005 | 1.00 | ALDH1A1 (0.46) | ALDH1A1ERN1ALDH5A1ABATLCK | |
| SCHEMBL4575600 | 0.82 | ALDH5A1 (0.52) | ALDH1A1ALDH5A1ABATLCKKDM4E | |
| SCHEMBL9261197 | 0.82 | LCK (0.58) | ALDH1A1ALDH5A1ABATLCKKDM4E | |
| SCHEMBL708554 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ERN1ALDH5A1ABATKDM4E | |
| SCHEMBL646947 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ERN1ALDH5A1ABATKDM4E | |
| SCHEMBL37131 | 0.82 | LCK (0.58) | ALDH1A1ALDH5A1ABATLCKKDM4E | |
| Potassium SCHEMBL31540630 | 0.79 | LCK (0.55) | ALDH1A1ALDH5A1ABATLCKKDM4E | |
| Phloroglucinol SCHEMBL28580013 | 0.76 | ALDH5A1 (0.52) | ALDH1A1ALDH5A1ABATLCKKDM4E | |
| SCHEMBL16955787 | 0.76 | LCK (0.40) | ALDH1A1LCKKDM4EPTGS2RAB9A | |
| SCHEMBL25180638 | 0.73 | KDM4E (0.53) | ALDH1A1LCKKDM4EPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565562-A1 | PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES | Nxera Pharma UK Limited (GB) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024028603-A1 | PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-02-08 | — | — | WO | disclosed |