Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18919446 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CASP3SLC18A3TSHRMEN1 | |
| SCHEMBL10495293 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2TSHRMEN1KMT2AGAA | |
| SCHEMBL18919421 | 0.77 | GAA (0.41) | CASP3TSHRKMT2AGAAPOLB | |
| SCHEMBL18919411 | 0.75 | HEXA (0.44) | TSHRGAA | |
| SCHEMBL10830513 | 0.74 | ALDH1A1 (0.52) | SMN1; SMN2CASP3SLC18A3TSHRGAA | |
| SCHEMBL21909067 | 0.73 | CDK8 (0.36) | SMN1; SMN2CASP3TSHRKMT2AGAA | |
| Trifluoroacetic Acid SCHEMBL21828450 | 0.72 | LCK (0.36) | CASP3POLB | |
| SCHEMBL18470154 | 0.72 | ALDH1A1 (0.57) | SMN1; SMN2TSHRMEN1KMT2AGAA | |
| SCHEMBL20574374 | 0.71 | POLB (0.48) | CASP3TSHRMEN1KMT2AGAA | |
| SCHEMBL18942729 | 0.71 | AKT1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914240-B | Norbornenone compounds releasing carbon monoxide | 奥塔哥创新有限公司 | 2024-02-20 | — | — | CN | disclosed |