Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556978 | 1.00 | RPS6KA5 (0.52) | RPS6KA5MAPTSMN1; SMN2RPS6KA4ABL1 | |
| SCHEMBL30753606 | 0.79 | RPS6KA5 (0.47) | RPS6KA5MAPTSMN1; SMN2POLB | |
| SCHEMBL22557590 | 0.79 | RPS6KA5 (0.47) | RPS6KA5MAPTSMN1; SMN2POLB | |
| SCHEMBL5090434 | 0.77 | RPS6KA5 (0.68) | RPS6KA5MAPTSMN1; SMN2RPS6KA4MKNK1 | |
| SCHEMBL19533518 | 0.69 | MKNK1 (0.49) | RPS6KA5MAPTSMN1; SMN2RPS6KA4ABL1 | |
| SCHEMBL27253708 | 0.69 | RPS6KA5 (0.57) | RPS6KA5MAPTSMN1; SMN2RPS6KA4MKNK1 | |
| SCHEMBL21282714 | 0.67 | RPS6KA5 (0.60) | RPS6KA5MAPTSMN1; SMN2RPS6KA4ALDH1A1 | |
| SCHEMBL31205699 | 0.65 | RPS6KA5 (0.52) | RPS6KA5MAPTSMN1; SMN2RPS6KA4ALDH1A1 | |
| SCHEMBL16140670 | 0.65 | RPS6KA5 (0.67) | RPS6KA5MAPTRPS6KA4MKNK1MKNK2 | |
| SCHEMBL29190539 | 0.64 | ALDH1A1 (0.36) | RPS6KA5MAPTSMN1; SMN2POLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710664-B | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2024-01-26 | — | — | CN | disclosed |