Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753716 | 0.93 | HDAC6 (0.48) | MEN1KMT2AHDAC6HDAC1HDAC2 | |
| SCHEMBL30753713 | 0.91 | BDKRB2 (0.46) | POLBHDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL30753732 | 0.89 | TRPV1 (0.49) | MEN1KMT2AHDAC6HDAC1HDAC2 | |
| SCHEMBL30753708 | 0.89 | HDAC1 (0.41) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL30753699 | 0.88 | LTA4H (0.51) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL30753730 | 0.80 | MC4R (0.45) | POLBMEN1KMT2A | |
| SCHEMBL1244207 | 0.79 | SCN9A (0.51) | POLBMEN1KMT2AHDAC6HDAC1 | |
| SCHEMBL30753720 | 0.79 | RAB9A (0.47) | POLBMEN1KMT2A | |
| SCHEMBL30753700 | 0.79 | SMN1; SMN2 (0.47) | POLBMEN1KMT2A | |
| SCHEMBL1244196 | 0.79 | BDKRB2 (0.48) | HDAC6HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486762-A | Novel compound and use method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-02-02 | — | — | CN | disclosed |