Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.49 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.49 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.49 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.49 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.49 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.49 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.49 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.49 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753716 | 0.91 | HDAC6 (0.48) | SCN9AHDAC1HDAC4HDAC2HDAC6 | |
| SCHEMBL30753729 | 0.89 | POLB (0.48) | TRPV1SCN9AHDAC1HDAC4HDAC2 | |
| SCHEMBL30753713 | 0.88 | BDKRB2 (0.46) | TRPV1SCN9AHDAC1HDAC4HDAC2 | |
| SCHEMBL30753715 | 0.88 | RAB9A (0.44) | TRPV1MEN1KMT2A | |
| SCHEMBL30753708 | 0.86 | HDAC1 (0.41) | TRPV1SCN9AHDAC1HDAC4HDAC2 | |
| SCHEMBL30753699 | 0.86 | LTA4H (0.51) | SCN9AHDAC1HDAC4HDAC2HDAC6 | |
| SCHEMBL1245446 | 0.79 | BDKRB2 (0.46) | TRPV1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL7857107 | 0.79 | MMP9 (0.46) | TRPV1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL30753730 | 0.78 | MC4R (0.45) | MEN1KMT2A | |
| SCHEMBL30753712 | 0.78 | RAB9A (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486762-A | Novel compound and use method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-02-02 | — | — | CN | disclosed |