SCHEMBL30758015

SCHEMBL30758015

O=[PH](OO)OCc1ccc(Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.45
AGXT P21549 2/20 0.45
NR4A2 P43354 1/20 0.41
MAOB P27338 4/20 0.40
MAOA P21397 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
KMT2A Q03164 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
APP P05067 1/20 0.38
P2RX4 Q99571 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17181662 0.88 IDO1 (0.52) IDO1AGXTNR4A2MAOBMAOA
SCHEMBL9818255 0.80 TSHR (0.44) IDO1AGXTNR4A2CA1CA2
SCHEMBL17181663 0.80 IDO1 (0.48) IDO1AGXTNR4A2MAOBMAOA
SCHEMBL8855401 0.73 IDO1 (0.50) IDO1CA2KMT2AAPPALDH1A1
SCHEMBL5079158 0.72 IDO1 (0.58) IDO1AGXTNR4A2MAOBMAOA
SCHEMBL742829 0.69 ALDH1A1 (0.46) MAOBMAOACA2CA9KMT2A
SCHEMBL498363 0.68 ALDH1A1 (0.49) IDO1AGXTNR4A2MAOBMAOA
SCHEMBL10598741 0.68 MAOB (0.34) IDO1AGXTMAOBCA2CA9
SCHEMBL29286607 0.68 TAAR1 (0.50) IDO1AGXTMAOBMAOATAAR1
SCHEMBL8716806 0.68 IDO1 (0.58) IDO1AGXTNR4A2MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115385784-B Preparation method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone 顺毅股份有限公司 2024-02-13 CN claimed
CN-115385784-B Preparation method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone 顺毅股份有限公司 2024-02-13 CN disclosed