SCHEMBL17181663

SCHEMBL17181663

O=[PH](O)OCc1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.48
AGXT P21549 2/20 0.48
APP P05067 1/20 0.44
NR4A2 P43354 2/20 0.43
MAOB P27338 4/20 0.42
MAOA P21397 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
KMT2A Q03164 3/20 0.41
TAAR1 Q96RJ0 1/20 0.40
MEN1 O00255 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22589820 0.83 IDO1 (0.48) IDO1APPCA2KMT2ATAAR1
SCHEMBL17181662 0.83 IDO1 (0.52) IDO1AGXTAPPNR4A2MAOB
SCHEMBL4076437 0.81 APP (0.46) IDO1APPMAOBMAOACA2
SCHEMBL3365610 0.81 PRSS1 (0.39) IDO1APPCA1CA2CA9
SCHEMBL17061043 0.81 CYP3A4 (0.50) IDO1APP
SCHEMBL10598745 0.80 ALDH1A1 (0.33) IDO1MAOBCA2KMT2ATAAR1
SCHEMBL30758015 0.80 IDO1 (0.45) IDO1AGXTAPPNR4A2MAOB
SCHEMBL4938371 0.79 IDO1 (0.48) IDO1APPMAOBMAOACA1
SCHEMBL4055238 0.79 IDO1 (0.48) IDO1AGXTAPPNR4A2MAOB
SCHEMBL4066062 0.79 CES2 (0.38) IDO1APPCA2CA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115385784-B Preparation method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone 顺毅股份有限公司 2024-02-13 CN claimed
CN-114195625-B Preparation method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone 江苏剑牌农化股份有限公司 2023-12-01 CN claimed
CN-110734364-B Synthesis method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone 上海生农生化制品股份有限公司 2022-09-23 CN claimed
CN-114195625-A Preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone 江苏剑牌农化股份有限公司 2022-03-18 CN claimed
CN-110734364-A Synthesis method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone 上海生农生化制品股份有限公司 2020-01-31 CN claimed
CN-106279264-B A kind of preparation method of alpha-alkoxy base p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2019-05-24 CN claimed
CN-106279275-B A kind of process for catalytic synthesis of alpha-alkoxy base p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2018-11-13 CN claimed
CN-106279275-A A kind of process for catalytic synthesis of α alkoxyl p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2017-01-04 CN claimed
CN-106279264-A A kind of preparation method of α alkoxyl p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2017-01-04 CN claimed
US-9227900-B2 Method for preparing 1-(4-chlorophenyl)-2-cyclopropyl-1-propanone and intermediate thereof JIANGSU CHENGYANG CROP SCIENCE CO., LTD. (CN) 2016-01-05 US claimed
US-20150299078-A1 METHOD FOR PREPARING 1-(4-CHLOROPHENYL)-2-CYCLOPROPYL-1-PROPANONE AND INTERMEDIATE THEREOF JIANGSU CHENGYANG CROP SCIENCE CO., LTD. (CN) 2015-10-22 US claimed
CN-119119705-A Polycarbonate resin film 三菱化学株式会社 2024-12-13 CN disclosed
CN-119119704-A Polycarbonate resin film 三菱化学株式会社 2024-12-13 CN disclosed
CN-112805267-B Carboxamide and sulfonamide derivatives as TEAD modulators 豪夫迈·罗氏有限公司 2024-03-08 CN disclosed
CN-115385784-B Preparation method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone 顺毅股份有限公司 2024-02-13 CN disclosed
CN-106279264-A A kind of preparation method of α alkoxyl p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2017-01-04 CN disclosed
CN-106279264-A A kind of preparation method of α alkoxyl p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2017-01-04 CN disclosed
CN-106279264-A A kind of preparation method of α alkoxyl p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2017-01-04 CN disclosed
US-9227900-B2 Method for preparing 1-(4-chlorophenyl)-2-cyclopropyl-1-propanone and intermediate thereof JIANGSU CHENGYANG CROP SCIENCE CO., LTD. (CN) 2016-01-05 US disclosed
US-20150299078-A1 METHOD FOR PREPARING 1-(4-CHLOROPHENYL)-2-CYCLOPROPYL-1-PROPANONE AND INTERMEDIATE THEREOF JIANGSU CHENGYANG CROP SCIENCE CO., LTD. (CN) 2015-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299078-A1 METHOD FOR PREPARING 1-(4-CHLOROPHENYL)-2-CYCLOPROPYL-1-PROPANONE AND INTERMEDIATE THEREOF PHKG2, PHKG1, HPD IDO1 3152/4885AGXT 3710/4885APP 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.