SCHEMBL5079158

SCHEMBL5079158

OOCc1ccc(Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.58
AGXT P21549 2/20 0.58
MAOB P27338 5/20 0.47
APP P05067 1/20 0.47
NR4A2 P43354 1/20 0.46
MAOA P21397 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
MMP2 P08253 2/20 0.43
MMP1 P03956 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4995796 0.78 IDO1 (0.64) IDO1AGXTMAOBAPPNR4A2
SCHEMBL13021169 0.78 IDO1 (0.59) IDO1APPCA1CA2CA9
SCHEMBL357428 0.78 IDO1 (0.64) IDO1AGXTMAOBAPPNR4A2
SCHEMBL9821418 0.76 IDO1 (0.61) IDO1AGXTMAOBAPPNR4A2
SCHEMBL8995755 0.76 IDO1 (0.61) IDO1AGXTMAOBAPPNR4A2
SCHEMBL3328218 0.75 IDO1 (0.54) IDO1AGXTMAOBAPPNR4A2
SCHEMBL28544358 0.75 TAAR1 (0.50) IDO1AGXTMAOBTAAR1
SCHEMBL11786079 0.74 LPL (0.46) IDO1CA2ALDH1A1CYP2C19L3MBTL1
SCHEMBL14899719 0.74 ALDH1A1 (0.50) IDO1MAOBAPPMAOAALDH1A1
SCHEMBL31273 0.74 IDO1 (0.58) IDO1AGXTMAOBAPPMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1533108-B1 Pneumatic tire with built-in colored sealant layer and method of preparing said pneumatic tire GOODYEAR TIRE & RUBBER (US) 2012-09-26 EP claimed
EP-1457308-B1 Pneumatic tire having built-in sealant layer and preparation thereof GOODYEAR TIRE & RUBBER (US) 2008-10-01 EP claimed
EP-1721932-B1 Pneumatic tire with built-in sealant containing pre-hydrophobated silica GOODYEAR TIRE & RUBBER (US) 2008-08-13 EP claimed
CN-119552056-A Metalloporphyrin catalytic O without tail gas emission based on continuous flow tubular reaction2Method for oxidizing hydrocarbon compounds 浙江工业大学 2025-03-04 CN disclosed
CN-111675620-A Method for catalytic oxidation of toluene and derivatives thereof by metalloporphyrin 浙江工业大学 2020-09-18 CN disclosed
EP-3374364-B1 USE OF BORON FORMATES FOR REDUCING UNSATURATED ORGANIC FUNCTIONS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2020-04-01 EP disclosed
US-10273250-B2 Use for boron formates for reducing unsaturated organic functions COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2019-04-30 US disclosed
US-20180327429-A1 Use for Boron Formates for Reducing Unsaturated Organic Functions COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2018-11-15 US disclosed
EP-3374364-A1 USE OF BORON FORMATES FOR REDUCING UNSATURATED ORGANIC FUNCTIONS Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2018-09-19 EP disclosed
US-8309733-B2 Imino derivatives, methods for producing the same and insecticides containing the same Meji Seika Pharma Co., Ltd. (JP) 2012-11-13 US disclosed
US-20110172433-A1 NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME MEIJI SEIKA KAISHA, LTD. (JP) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180327429-A1 Use for Boron Formates for Reducing Unsaturated Organic Functions BCHE, C9, PFAS IDO1 3134/4885AGXT 2928/4885MAOB 66/4885
US-10273250-B2 Use for boron formates for reducing unsaturated organic functions BCHE, PFAS, C9 IDO1 2865/4885AGXT 2648/4885MAOB 59/4885
US-20110172433-A1 NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME CNOT9, CBR1, CBR3 IDO1 1002/4885AGXT 814/4885MAOB 3098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.