SCHEMBL30758166

SCHEMBL30758166

Cc1nc2c(F)cc(B3OC(C)(C)C(C)(C)O3)cc2c(C)c1C(C)O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
EGFR P00533 1/20 0.31
ROCK1 Q13464 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24619120 0.79 IDO1 (0.33) IDO1TDO2LPLLIPGEGFR
SCHEMBL17421129 0.78 LPL (0.42) LPLLIPGROCK1
SCHEMBL17421109 0.76 LPL (0.38) LPLLIPGEGFRROCK1
SCHEMBL29684289 0.73 LPL (0.34) IDO1TDO2LPLLIPGEGFR
SCHEMBL24619212 0.73 LPL (0.34) IDO1TDO2LPLLIPGEGFR
SCHEMBL30242645 0.73 LIPG (0.38) LPLLIPGROCK1
SCHEMBL24012521 0.73 LIPG (0.38) LPLLIPGROCK1
SCHEMBL30758151 0.73 LMNA (0.34)
SCHEMBL24619607 0.73 EGFR (0.35) IDO1TDO2LPLLIPGEGFR
SCHEMBL28342624 0.71 EGFR (0.41) IDO1TDO2LPLLIPGEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562000-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc (US) 2025-06-04 EP disclosed
WO-2024022487-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc (US) 2024-02-01 WO disclosed