SCHEMBL30758151

SCHEMBL30758151

Cc1nc2c(F)cc(Br)cc2c(C)c1C(C)O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
PRNP P04156 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
NOD2 Q9HC29 1/20 0.34
OPRM1 P35372 1/20 0.31
OPRK1 P41145 1/20 0.31
EPRS1 P07814 1/20 0.30
NQO2 P16083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6076918 0.74 PRNP (0.41) LMNAPRNPHPGDHTTNPSR1
SCHEMBL24619094 0.74 L3MBTL1 (0.40) LMNAHTTNPSR1
SCHEMBL30758166 0.73 IDO1 (0.32)
SCHEMBL30758287 0.73 ALDH1A1 (0.47) LMNAPRNPHPGDHTTNPSR1
SCHEMBL2144930 0.72 GABRA1 (0.38) HTTNPSR1
SCHEMBL30758149 0.71 CCND3 (0.35)
SCHEMBL17420920 0.70 GABRA1 (0.33)
SCHEMBL18450611 0.69 RXFP1 (0.36) LMNAPRNPHPGDHTTNPSR1
SCHEMBL18450035 0.69 PRNP (0.39) LMNAPRNPHPGDHTTNPSR1
SCHEMBL23119104 0.67 L3MBTL1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562000-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc (US) 2025-06-04 EP disclosed
CN-119630652-A Amino heteroaryl kinase inhibitors 安锐生物医药公司 2025-03-14 CN disclosed
WO-2024022487-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc (US) 2024-02-01 WO disclosed