SCHEMBL30758201

SCHEMBL30758201

Cc1nc2c(cnc3ccc(Cl)cc32)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
TYMS P04818 1/20 0.47
HTT P42858 1/20 0.45
PIM1 P11309 1/20 0.44
PIM2 Q9P1W9 1/20 0.44
PTGES O14684 1/20 0.41
PARP1 P09874 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29339070 0.78 ALDH1A1 (0.46) ALDH1A1PTGESPARP1
SCHEMBL2884316 0.73 ALDH1A1 (1.00) ALDH1A1TYMSHTT
SCHEMBL405016 0.71 ALDH1A1 (0.50) ALDH1A1TYMSHTTPIM1PIM2
SCHEMBL2884818 0.70 ALDH1A1 (0.72) ALDH1A1TYMSHTT
SCHEMBL5313770 0.68 LMNA (0.57) ALDH1A1TYMSPIM1PIM2
SCHEMBL5313776 0.68 TYMS (0.72) ALDH1A1TYMSPIM1PIM2PARP1
SCHEMBL31463101 0.68 TYMS (0.72) ALDH1A1TYMSPIM1PIM2PARP1
SCHEMBL12066505 0.67 LMNA (0.56) ALDH1A1HTTPARP1
SCHEMBL22304342 0.66 NR4A2 (0.51) ALDH1A1PARP1
SCHEMBL557085 0.66 MET (0.42) ALDH1A1PIM1PIM2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562000-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc (US) 2025-06-04 EP disclosed
CN-119630652-A Amino heteroaryl kinase inhibitors 安锐生物医药公司 2025-03-14 CN disclosed
WO-2024022487-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc (US) 2024-02-01 WO disclosed