SCHEMBL557085

SCHEMBL557085

Clc1cnc2ccc3ccc(Cl)nc3c2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MET P08581 1/20 0.42
NR4A2 P43354 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.34
PARP1 P09874 1/20 0.34
SLC40A1 Q9NP59 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRA6 Q16445 1/20 0.33
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
PIM1 P11309 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
EGFR P00533 1/20 0.32
IDO1 P14902 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15551629 0.75 ALDH1A1 (0.45) METNR4A2NPC1LMNAPDGFRB
SCHEMBL28938002 0.74 MET (0.35) METNPC1LMNAALDH1A1
SCHEMBL1669125 0.73 LMNA (0.67) NR4A2NPC1LMNAALDH1A1
SCHEMBL29237023 0.70 PDGFRB (0.41) METNR4A2NPC1LMNAPDGFRB
SCHEMBL30969486 0.70 PDGFRB (0.41) METNR4A2NPC1LMNAPDGFRB
SCHEMBL4317048 0.70 MET (0.56) METPARP1GABRA1GABRG2GABRB3
SCHEMBL4308502 0.68 MET (0.48) METPARP1GABRA1GABRG2GABRB3
SCHEMBL557084 0.68 CCR1 (0.43) LMNASLC40A1PIM1PIM2IDO1
SCHEMBL29533844 0.68 CCR1 (0.43) LMNASLC40A1PIM1PIM2IDO1
SCHEMBL10203085 0.68 MET (0.58) METNPC1LMNAGABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107586296-B Preparation method and application of 2, 9-diaryl substituted phenanthroline and iron complex thereof 南开大学 2023-05-02 CN claimed
CN-110028504-A The preparation method and applications of phenanthroline and its cobalt complex that 2,9- diaryl replaces 南开大学 2019-07-19 CN claimed
CN-107586296-A The preparation method and applications of the phenanthroline and its iron complex of the substitution of 2,9 diaryl 南开大学 2018-01-16 CN claimed
US-4777261-A Preparation of 2-benzoxazolones SHELL OIL COMPANY (US) 1988-10-11 US claimed
CN-115894494-B Ligand, complex and application thereof in electrochemical reaction 南方科技大学 2024-06-18 CN disclosed
CN-114249725-B Preparation method and application of 2-imine-9-aryl substituted phenanthroline and iron complex thereof 南开大学 2024-05-07 CN disclosed
CN-114249725-B Preparation method and application of 2-imine-9-aryl substituted phenanthroline and iron complex thereof 南开大学 2024-05-07 CN disclosed
CN-117327064-A Disubstituted phenanthroline compound and application thereof 烟台显华科技集团股份有限公司 2024-01-02 CN disclosed
CN-117327100-A Diphenanthroline substituted compound and application thereof 烟台显华科技集团股份有限公司 2024-01-02 CN disclosed
CN-113321649-B Compound, electron transport material and organic electroluminescent device 烟台显华化工科技有限公司 2023-05-30 CN disclosed
CN-107586296-B Preparation method and application of 2, 9-diaryl substituted phenanthroline and iron complex thereof 南开大学 2023-05-02 CN disclosed
CN-107586296-B Preparation method and application of 2, 9-diaryl substituted phenanthroline and iron complex thereof 南开大学 2023-05-02 CN disclosed
EP-0231045-B1 A PROCESS FOR THE PREPARATION OF CARBAMATES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-05-27 EP disclosed
EP-0224292-B1 PROCESS FOR THE PREPARATION OF ORGANIC ISOCYANATES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-04-11 EP disclosed
EP-0339973-A1 Substituted 1,10-phenanthrolines EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-11-02 EP disclosed
WO-1989010366-A1 SUBSTITUTED 1,10-PHENANTHROLINES EASTMAN KODAK COMPANY (US) 1989-11-02 WO disclosed
US-4777261-A Preparation of 2-benzoxazolones SHELL OIL COMPANY (US) 1988-10-11 US disclosed
EP-0255744-A1 A process for the preparation of 2-benzoxazolones SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-02-10 EP disclosed
EP-0231045-A2 A process for the preparation of carbamates SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-08-05 EP disclosed
EP-0224292-A1 Process for the preparation of organic isocyanates SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-06-03 EP disclosed