Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.43 |
| ▸ | LOX | P28300 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20490853 | 1.00 | ALDH1A1 (0.50) | ALDH1A1POLBL3MBTL1LOXL2LOX | |
| SCHEMBL9106409 | 0.85 | ALDH1A1 (0.46) | ALDH1A1POLBL3MBTL1LOXL2LOX | |
| SCHEMBL28582634 | 0.81 | LOXL2 (0.70) | LOXL2LOX | |
| SCHEMBL875110 | 0.80 | ALOX5AP (0.43) | ALDH1A1POLBL3MBTL1SCN9ASCN7A | |
| SCHEMBL15871857 | 0.78 | LOXL2 (0.55) | ALDH1A1LOXL2LOXSCN9ASCN7A | |
| SCHEMBL18003561 | 0.77 | MAOA (0.48) | ALDH1A1POLBL3MBTL1MAPTMAOA | |
| SCHEMBL875626 | 0.76 | SCN9A (0.39) | ALDH1A1POLBL3MBTL1SCN9AMAPT | |
| SCHEMBL1011342 | 0.75 | ALDH1A1 (0.72) | ALDH1A1POLBL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL18003267 | 0.75 | GPR52 (0.40) | ALDH1A1POLBL3MBTL1MAOAMAOB | |
| SCHEMBL417140 | 0.74 | ALDH1A1 (0.63) | ALDH1A1POLBL3MBTL1MAPTSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736178-B | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-117736178-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117510468-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117466868-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-01-30 | — | — | CN | disclosed |