SCHEMBL30759248

SCHEMBL30759248

CC(C)(C)OC(=O)NCc1cc2ncccc2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 1/20 0.49
▸ MTNR1A P48039 2/20 0.42
▸ MTNR1B P49286 2/20 0.42
▸ KDM4A O75164 1/20 0.42
▸ NAMPT P43490 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ CACNA1H O95180 1/20 0.41
▸ CACNA1B Q00975 1/20 0.41
▸ CACNA1C Q13936 1/20 0.41
▸ DAO P14920 1/20 0.41
▸ ATAD2 Q6PL18 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ NR3C1 P04150 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ PTPN1 P18031 1/20 0.40
▸ AKT1 P31749 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ PRMT5 O14744 2/20 0.39
▸ WDR77 Q9BQA1 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25587553 0.84 DAO (0.43) MTNR1AMTNR1BCACNA1BDAOATAD2
SCHEMBL24016459 0.82 MTNR1A (0.56) MTNR1AMTNR1BL3MBTL1DAOATAD2
SCHEMBL30759266 0.81 KDM4A (0.48) BCHEKDM4ANAMPTL3MBTL1CACNA1H
SCHEMBL23436429 0.81 SMN1; SMN2 (0.51) BCHEKDM4AL3MBTL1CACNA1HCACNA1B
SCHEMBL27144888 0.80 DAO (0.48) MTNR1AMTNR1BKDM4ADAOATAD2
SCHEMBL30469092 0.80 KDM4A (0.54) BCHEMTNR1AMTNR1BKDM4ACACNA1H
SCHEMBL25677972 0.80 KDM4A (0.54) BCHEMTNR1AMTNR1BKDM4ACACNA1H
SCHEMBL25434377 0.80 BCHE (0.46) BCHEKDM4AL3MBTL1CACNA1HCACNA1B
SCHEMBL31609617 0.80 BCHE (0.46) BCHEKDM4AL3MBTL1CACNA1HCACNA1B
SCHEMBL31751652 0.77 SMN1; SMN2 (0.44) BCHEMTNR1AMTNR1BKDM4ANAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 — — US disclosed
WO-2024044098-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C9, SSB, C1S BCHE 455/4885MTNR1A 2121/4885MTNR1B 1594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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