Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23478663 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL30632885 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL30759248 | 0.77 | BCHE (0.49) | SMN1; SMN2MTNR1AMTNR1BL3MBTL1CACNA1H | |
| SCHEMBL23436429 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1CACNA1HCACNA1BCACNA1C | |
| SCHEMBL19249105 | 0.76 | CTSV (0.46) | SMN1; SMN2MTNR1AMTNR1BL3MBTL1CACNA1H | |
| SCHEMBL30967628 | 0.76 | CKS1B (0.37) | ATRBCHEPARP1KDM4EPOLB | |
| SCHEMBL19964841 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL16808752 | 0.74 | MTNR1A (0.47) | SMN1; SMN2MTNR1AMTNR1BCACNA1HCACNA1B | |
| SCHEMBL30469092 | 0.74 | KDM4A (0.54) | SMN1; SMN2MTNR1AMTNR1BCACNA1HCACNA1B | |
| SCHEMBL25677972 | 0.74 | KDM4A (0.54) | SMN1; SMN2MTNR1AMTNR1BCACNA1HCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264954-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-12-26 | — | — | WO | disclosed |