Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25434377 | 1.00 | BCHE (0.46) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL23436429 | 0.87 | SMN1; SMN2 (0.51) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL30552716 | 0.81 | CACNA1H (0.43) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL25433834 | 0.81 | CACNA1H (0.43) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL19964551 | 0.81 | SMN1; SMN2 (0.55) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL30759248 | 0.80 | BCHE (0.49) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL22013237 | 0.79 | CACNA1H (0.53) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL22790414 | 0.78 | CACNA1G (0.43) | BCHECACNA1BCACNA1CGRM2 | |
| SCHEMBL23731881 | 0.77 | CACNA1H (0.47) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL30130048 | 0.77 | SMN1; SMN2 (0.56) | BCHESMN1; SMN2CACNA1HCACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482583-B1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2026-04-01 | — | — | EP | disclosed |
| US-20250179066-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179066-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | MRPL21, WIZ, CFTR | BCHE 3763/4885SMN1; SMN2 3678/4885CACNA1H 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.