Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 5/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31754252 | 0.82 | KISS1R (0.45) | KISS1ROPRM1LNPEP | |
| SCHEMBL30519203 | 0.79 | MME (0.54) | GPR132ACEMMECMKLR2CMKLR1 | |
| SCHEMBL31754347 | 0.79 | SLC7A5 (0.49) | GRIA1LNPEP | |
| SCHEMBL30759465 | 0.79 | LMNA (0.37) | OPRM1LNPEP | |
| SCHEMBL30759431 | 0.79 | KLKB1 (0.36) | GRIA1KISS1RLNPEP | |
| SCHEMBL31754274 | 0.78 | FOLH1 (0.48) | GPR132MMECMKLR2CMKLR1 | |
| SCHEMBL30759471 | 0.77 | KISS1R (0.42) | KISS1ROPRM1LNPEP | |
| SCHEMBL30019030 | 0.76 | ERAP2 (0.48) | GPR132KISS1RLNPEP | |
| SCHEMBL29816805 | 0.75 | KISS1R (0.52) | GPR132ACEMMEKISS1ROPRM1 | |
| SCHEMBL30845376 | 0.75 | NPY1R (0.56) | ACEKISS1ROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558513-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | Merck Sharp & Dohme LLC (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020159-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | MERCK SHARP & DOHME LLC (US) | 2024-01-25 | — | — | WO | disclosed |