SCHEMBL30759555

SCHEMBL30759555

COc1cc2c(cc1-c1cncc(C#N)c1)-c1c(c(C(=O)N3CCCN(C)CC3)nn1-c1cc(Cl)cc(Cl)c1)CC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ UGCG Q16739 1/20 0.38
▸ TLR8 Q9NR97 2/20 0.36
▸ TLR7 Q9NYK1 2/20 0.36
▸ IKBKB O14920 3/20 0.35
▸ BRD4 O60885 1/20 0.34
▸ CREBBP Q92793 1/20 0.34
▸ AURKA O14965 1/20 0.34
▸ CCNA2 P20248 1/20 0.34
▸ CDK2 P24941 1/20 0.34
▸ TTK P33981 1/20 0.34
▸ CCNA1 P78396 1/20 0.34
▸ PIK3CD O00329 4/20 0.34
▸ PIK3R2 O00459 4/20 0.34
▸ PIK3CA P42336 4/20 0.34
▸ PIK3CB P42338 4/20 0.34
▸ PIK3CG P48736 4/20 0.34
▸ PIK3R5 Q8WYR1 4/20 0.34
▸ PIK3R3 Q92569 4/20 0.34
▸ CYP11B2 P19099 2/20 0.34
▸ CYP11B1 P15538 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27120267 1.00 UGCG (0.38) UGCGTLR8TLR7IKBKBBRD4
SCHEMBL27120270 0.89 IKBKB (0.39) UGCGTLR8TLR7IKBKBAURKA
SCHEMBL30759621 0.89 IKBKB (0.39) UGCGTLR8TLR7IKBKBAURKA
SCHEMBL30759574 0.86 CCNA2 (0.38) IKBKBBRD4CREBBPCCNA2CDK2
SCHEMBL27119953 0.86 CCNA2 (0.38) IKBKBBRD4CREBBPCCNA2CDK2
SCHEMBL27122184 0.84 IKBKB (0.36) IKBKBCCNA2CDK2CCNA1PIK3CD
SCHEMBL30759686 0.83 GRM5 (0.37) IKBKBBRD4CREBBPPIK3CDPIK3R2
SCHEMBL27119422 0.83 GRM5 (0.37) IKBKBBRD4CREBBPPIK3CDPIK3R2
SCHEMBL30759597 0.82 PDE7A (0.36) IKBKBBRD4CREBBPCCNA2CDK2
SCHEMBL27119775 0.82 PDE7A (0.36) IKBKBBRD4CREBBPCCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR UGCG 2294/4885TLR8 1411/4885TLR7 1262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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