SCHEMBL30759557

SCHEMBL30759557

CC1(C)C(=O)NCCN1C(=O)c1nn(-c2ccccn2)c2c1OCc1ccc(Br)cc1-2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ CCNA2 P20248 1/20 0.34
▸ CDK2 P24941 1/20 0.34
▸ CCNA1 P78396 1/20 0.34
▸ PIK3CD O00329 1/20 0.33
▸ PIK3R2 O00459 1/20 0.33
▸ PIK3CA P42336 1/20 0.33
▸ PIK3CB P42338 1/20 0.33
▸ PIK3CG P48736 1/20 0.33
▸ PIK3R5 Q8WYR1 1/20 0.33
▸ PIK3R3 Q92569 1/20 0.33
▸ SLC11A2 P49281 1/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ CNR2 P34972 1/20 0.32
▸ MAPT P10636 2/20 0.31
▸ KDM4E B2RXH2 2/20 0.31
▸ HSD17B10 Q99714 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27126703 1.00 SMN1; SMN2 (0.35) SMN1; SMN2CCNA2CDK2CCNA1PIK3CD
SCHEMBL27126549 0.87 CYP11B2 (0.35) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL30759605 0.87 CYP11B2 (0.35) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL27126007 0.84 SMN1; SMN2 (0.35) SMN1; SMN2CCNA2CDK2CCNA1PIK3CD
SCHEMBL30759616 0.84 SMN1; SMN2 (0.35) SMN1; SMN2CCNA2CDK2CCNA1PIK3CD
SCHEMBL31758910 0.80 CCNA2 (0.40) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL27126584 0.80 CCNA2 (0.40) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL27126581 0.79 ALDH1A1 (0.44) SMN1; SMN2CCNA2CDK2CCNA1KMT2A
SCHEMBL30759556 0.79 ALDH1A1 (0.44) SMN1; SMN2CCNA2CDK2CCNA1KMT2A
SCHEMBL30759539 0.76 CCNA2 (0.39) CCNA2CDK2CCNA1PIK3CDPIK3R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR SMN1; SMN2 3474/4885CCNA2 2070/4885CDK2 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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